Cholesterol Metabolism
نویسندگان
چکیده
منابع مشابه
Cholesterol metabolism.
Because of the well established predictive association between plasma cholesterol concentration and ischaemic heart disease, we are apt to think of cholesterol as a harmful substance that we might be better without. It must be remembered, however, that cholesterol is essential for the normal functioning of the animal body. Herbivorous animals must satisfy all their requirements for cholesterol ...
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Hepatic cholesterol metabolism was examined in 27 Swedish patients with cholesterol gallstone disease and in 13 patients free of gallstones operated for roentgenographically suspect polyps in the gallbladder. All 40 patients underwent cholecystectomy, and a liver biopsy and gallbladder bile were obtained at surgery. The cholesterol saturation of gallbladder bile was significantly higher in pati...
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A study in mice implicates a cholesterol derivative in damping down the inflammatory response mediated by interleukin-1β and explaining, at least in part, the immunosuppressive effect of type I interferon, which is used in the treatment of multiple sclerosis.
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1. Abstract 2. Introduction 3. Discussion 3.1. ABC lipid transporters 3.1.2. Macrophage ABC lipid transporters 3.1.3. ABC transporter mediated lipid export from the liver 3.2. ABCA1 is a key regulator of HDL metabolism and cellular cholesterol and phospholipid export 3.2.1. ABCA1 mediated cholesterol trafficking and caveolae 3.2.2. ABCA1 and NPC1: two major regulators of cellular cholesterol tr...
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with a very short half-life relative to cholesterol. As a consequence they are present in very low concentrations in all mammalian systems, almost invariably accompanied by 103to 106-fold excess of cholesterol. Oxysterols are important intermediates in a number of hepatic and extrahepatic catabolic pathways, most of which generate water-soluble bile acids as final products. Based on largely ind...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1932
ISSN: 0035-9157
DOI: 10.1177/003591573202500474